This study examines the safety of a CBD-enriched herbal extract oil to see what effect it has on participants and their headaches.

We aimed to recruit 20 participants ages 14-17 who have been diagnosed with chronic headaches and have failed other treatments.

Participants administered CBD-enriched cannabis herbal extract oil twice per day, attended 7 in-clinic visits and completed daily electronic headache diaries.

June 2025 update

Recruitment has now closed.

We will share results when they become available.

This study is funded by SickKids.

This study is registered with ClinicalTrials.gov, NCT05337033.